Inhibition of glucose phosphorylation by mannoheptulose.
نویسندگان
چکیده
Felber, J. P. (1963). Experientia, 19, 227. Forsman, 0. & Gemzell, C. A. (1959). Acta endocr., Kbh., 32, 480. Gemzell, C. A. (1959). J. din. Endocrin. 19, 1049. Gibson, R. E., Ekstedt, R. D. & Stollerman, G. H. (1962). Fed. Proc. 21, 23. Glick, S. M., Roth, J., Yalow, R. S. & Berson, S. A. (1963). Nature, Lond., 199, 784. Greenspan, F. S., Cofell, J. A., Lew, W. & Peng, C. T. (1962). J. Lab. clin. Med. 59, 520. Greenwood, F. C., Hunter, W. M. & Glover, J. S. (1963). Biochem. J. 89, 114. Grodsky, G. M., Hayashida, T., Peng, C. T. & Geschwind, I. I. (1961). Proc. Soc. exp. Biol., N.Y., 107, 491. Grumbach, M. M. & Kaplan, S. L. (1962). Ciba Found. Colloq.: Endocrinology, 14, 63. Hales, C. N. & Randle, P. J. (1963). Biochem. J. 88, 137. Hayashida, T. & Li, C. H. (1958). Science, 128, 1276. Hunter, W. M. (1963). Analy8t, 88, 251. Hunter, W. M. & Greenwood, F. C. (1962a). Biochem. J. 85, 39P. Hunter, W. M. & Greenwood, F. C. (1962 b). Nature, Lond., 194, 495. Josimovich, J. B. & MacLaren, J. A. (1962). Endocrinology, 71, 209. Kohn, J. (1958). In The Protidee of Biological Fluids, vol. 5, p. 120. Ed. by Peeters, H. Amsterdam: Elsevier. Li, C. H., Moudgal, N. R. & Papkoff, H. (1960). J. biol. Chem. 285, 1038. Morgan, C. R. & Lazarow, A. (1962). Proc. Soc. exp. Biol., N.Y., 110, 29. Parker, M. L., Utiger, R. D. & Daughaday, W. H. (1962). J. din. Invest. 41, 262. Pastorelle, D. J. (1962). Surg. Forum, 13, 375. Raben, M. S. (1959). Recent Progr. Hormone Res. 15, 71. Read, C. H. & Bryan, G. T. (1960). Ciba Found. Colloq.: Endocrinology, 13, 68. Read, C. H., Eash, S. A. & Najjar, S. (1962). Ciba Found. Colloq.: Endocrinology, 14, 45. Read, C. H. & Stone, D. B. (1958). Amer. J. Di8. Child. 96, 538. Richter, M., Gold, J., Rankowicz, W. & Rose, B. (1962). Canad. J. Biochem. Physiol. 40, 35. Roth, J., Glick, S. M., Yalow, R. S. & Berson, S. A. (1963). Science, 140, 987. Trenkle, A., Moudgal, N. R., Sadri, K. K. & Li, C. H. (1961). Nature, Lond., 192, 260. Unger, R. H., Eisentraut, A. M., McCall, M. S., Keller, S., Lanz, H. C. & Madison, L. L. (1959). Proc. Soc. exp. Biol., N. Y., 102, 621. Utiger, R. D., Parker, M. L. & Daughaday, W. H. (1962). J. clin. Invest. 41, 254. Wolstenholme, G. E. W. & Cameron, M. P. (eds.) (1962). Ciba Found. Colloq.: Endocrinology, 14, 45-136. Yalow, R.S. & Berson, S.A. (1960). J. clin. Invest. 39, 1157.
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ورودعنوان ژورنال:
- The Biochemical journal
دوره 91 1 شماره
صفحات -
تاریخ انتشار 1964